Neuronal correlates of fear conditioning in the bed nucleus of the stria terminalis

The role of the bed nucleus of the stria terminalis in learning to fear.

Allopregnanolone in the bed nucleus of the stria terminalis modulates contextual fear in rats

Trauma- and stress-related disorders are among the most common types of mental illness affecting the U.S. population. For many of these disorders, there is a striking sex difference in lifetime prevalence; for instance, women are twice as likely as men to be affected by posttraumatic stress disorder (PTSD). Gonadal steroids and their metabolites have been implicated in sex differences in fear a...

The bed nucleus of the stria terminalis mediates inter-individual variations in anxiety and fear.

While learning to fear stimuli that predict danger promotes survival, the inability to inhibit fear to inappropriate cues leads to a pernicious cycle of avoidance behaviors. Previous studies have revealed large inter-individual variations in fear responding with clinically anxious humans exhibiting a tendency to generalize learned fear to safe stimuli or situations. To shed light on the origin ...

PS07. Neuronal encoding of anxiety in the bed nucleus of the stria terminalis

s | 3 reinstatement was accompanied by reduction of synaptic input in the IL. Then we hypothesized that prefrontal dopamine plays a key role in reinstatement and tested this idea. A reminder shock induced c-Fos expression in the IL-projecting dopaminergic neurons in the ventral tegmental area. Blocking of IL dopamine D1 receptor signaling prevented reduction of synaptic input, CeM c-Fos express...

اثرات داروهای هیستامینرژیک در bed nucleus of the stria terminalis (bnst) رت ها در تست elevated plus maze بر رفتارهای شبه اضطرابی

سیستم هیستامینرژیک مرکزی دارای تاثیرات تنظیمی بر رفتارهای شبه اضطرابی هم در حیوانات و هم در انسان است. این تاثیرات از طریق رسپتور h1 و h2 میانجیگری میشود. تست epm(elevatd plus-maze( برای بررسی تاثیرات اضطراب زایی یا اضطراب زدایی داروها در جوندگان بکار میرود. شواهد نشان می دهند که فعالیت (bnst) bed nucleus the stria terminalis رفتار شبه اضطرابی را در انسانها و حیوانات تنظیم می کند. در مطالعه حاض...